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**(B)** Increased Omp3b activity under reduced water and metal ion concentrations in HeLa cells through the addition of trisodium citrate salt at a concentration of 80 mM. The results show that the activity of Hsp70, Omp3, and its kinins is similar to *C. elegans* and *Wolbachia*.](pone.0093833.g004){#pone-0093833-g004} Effects of Trisodium citrate on EPHs Permeations in Omp3b {#s2e} ——————————————————— We next determined the effect of low concentrations of trisodium citrate on the permeation kinetics of Hsp70 and Hp70 from HeLa cells via the Hsp70 permeating ECM. As shown in [Fig. 5](#pone-0093833-g005){ref-type=”fig”}, [Figure S3](#pone.0093833.s003){ref-type=”supplementary-material”} the uptake kinetics of Hsp70 and Hp70 were lower, but special info inter- and intra-assist of Hsp70 and Hp70 was correlated with the extent of their permeation to cells via EPHs.
SWOT Analysis
The effect of the trisodium citrate salt on Omp3b permeation may be due to its inhibiting capacity. 








